Abstract: Objective To investigate the effect of CO2pneumoperitoneum pressure on acute gastrointestinal injury(AGI)in laparoscopic colorectal cancer resection．Methods 119 patients with colorectal cancer undergoing laparoscopic radical resection were selected from October 2010 to September 2016．According to the random number table method，they were divided into 3 groups．The intraoperative pneumoperitoneum pressure was set to 10mmHg，12mmHg and 15mmHg in group A，B，C respectively．Comparison of the three groups was carried out about intraoperative conditions，postoperative recoveries，plasma D-lactate levels and postoperative complications．Results There was no significant difference in the duration of operation，the amount of intraoperative blood loss，the duration of pneumoperitoneum，and postoperative first exhaust/defecation time among the three groups(P ＞0．05)．The levels of D-lactic acid in group C were significantly higher than that of group A and B 2 hours and 24 hours after operation(P ＜0．05)．There was no significant difference among the three groups in the incidence of postoperative complications(chylous leakage，anastomotic fistula，acute gastrointestinal injury，postoperative hemorrhage and intestinal paralysis)．Conclusion There is no significant effect of CO2pneumoperitoneum pressure on the appearance of acute gastrointestinal injury in the range of 10～15 mmHg during laparoscopic colorectal cancer resection．
韦维，黄许森，岑小宁，梁亮. 腹腔镜结直肠癌手术中CO2气腹压力对急性胃肠损伤的影响[J]. 中国现代手术学杂志, 2017, 21(2): 94-98.
WEI Wei. Effect of CO2Pneumoperitoneum Pressure on Acute Gastrointestinal Injury in Laparoscopic Surgery for Colorectal Cancer. Chinese Journal of Modern Operative Surgery, 2017, 21(2): 94-98.
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2017, Vol. 21 
