抽吸导管联合盐酸替罗非班在PCI治疗急性心肌梗塞中的临床疗效研究

doi:10.16260/j.cnki.1009-2188.2018.02.013

Chinese Journal of Modern Operative Surgery

2018, Vol. 22

Issue (2): 133-136 DOI: 10.16260/j.cnki.1009-2188.2018.02.013

Clinical Research

The Clinical Efficacy of the Thrombus Aspiration Catheter Combined with Tirofiban Hydrochloride in theInterventional Treatment of Acute Myocardial Infarction

LUO Rong, ZHU Xin-lin, YANG Wen-ting

Cardiology?Department,?No. 163?Central?Hospital?of?PLA，?The?Second?Affiliated?Hospital?of?Hunan?Normal?University,?Changsha?410003,?Hunan,?China

Abstract
Figure/Table
References
Related Citation (0)

Download:

HTML

PDF (193KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective　To evaluate the clinical application of GPⅡb/ Ⅲa receptor antagonist (Tirofiban hydrochloride injection)combined with the thrombus aspiration catheter in the percutaneous coronary intervention(PCI) treatment for acute myocardial infarction (AMI).　Methods　From January 2012 to October 2018, 80 patients with AMI planned for PCI treatments in our department were randomly divided into 2 groups, with 40 cases in each. Group A received PCI following thrombus aspiration catheter insertion and tirofiban hydrochloride injection. Group B received PCI following heparin anti-coagulation.　Results　In group A, stents were implanted in 35 cases after catheter suction. 5 cases who were injected with tirofiban returned to normal blood flow with mild stenosis and had no stents inserted after thrombus aspiration. And only 2 cases appeared no reflow phenomenon. In group B, 10 cases appeared no reflow phenomenon(P<0.05) after balloon expansion or stent implantation. In group A, the levels of CK-MB and TnI were lower than that of the control group(P<0.05). The incidence of malignant arrhythmia, cardiac death and recurrent myocardial infarction in group A were lower than that of the control group (P<0.05).　Conclusion　In the course of emergency PCI operation, thrombus aspiration catheter combined with Tirofiban hydrochloride injection can obviously reduce the incidence of no reflow phenomenon, reduce the occurrence of MACE, increase the myocardial perfusion and improve the clinical prognosis.

Key words： percutaneous coronary intervention 　aspiration catheter tirofiban hydrochloride

Published: 14 August 2018

ZTFLH:

R541.4

Corresponding Authors: ZHU Xin-lin

	Service
	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LUO?Rong

Cite this article:

LUO?Rong. The Clinical Efficacy of the Thrombus Aspiration Catheter Combined with Tirofiban Hydrochloride in theInterventional Treatment of Acute Myocardial Infarction[J]. Chinese Journal of Modern Operative Surgery, 2018, 22(2): 133-136.

URL:

http://www.surgerychina.com/EN/10.16260/j.cnki.1009-2188.2018.02.013 OR http://www.surgerychina.com/EN/Y2018/V22/I2/133