Chinese Journal of Modern Operative Surgery  2018, Vol. 22 Issue (4): 306-310 DOI: 10.16260/j.cnki.1009-2188.2018.04.017 |
| Clinical Research |
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| 23Gauge Miniinvasive Vitrectomy Combined with Adjunctive Triamcinolone Acetonide for Proliferative Diabetic Retinopathy#br# |
| ZHOU Lin, LI Fangfang#br#
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Department of Ophthalmology, The Second People's Hospital of Huai'an, Huai'an Affiliated Hospital of Xuzhou Medical University, Huai'an 223002, Jiangsu, China
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Abstract Abstract:ObjectiveTo study the safety and efficacy of 23gauge miniinvasive vitrectomy combined with posterior subTenoncapsule injection of triamcinolone acetonide in treating proliferative diabetic retinopathy (PDR).MethodsA total of 86 PDR patients with 95 eyes underwent 23G vitrectomy were analyzed retrospectively. According to therapeutic method, they were divided into two groups: 40 cases of 48 eyes were treated by pars plana vitrectomy combined with injection of triamcinolone acetonide (TA) as the combined group, and 8 mg of TA was injected into the eyes for dying of vitreous during the operations and 30 mg of TA was injected in the posterior subTenoncapsule. 46 cases of 47 eyes were performed direct vitrectomy as pure surgery group. The best corrected visual acuity(BCVA), intraocular pressure (IOP), changes of central macular thickness(CMT), and inflammation reaction of anterior chamber were compared between the two groups．ResultsAll cases were followed up for 6 months to 2 years with an average of 1.31±0.63 years. The BCVA and CMT of the both groups were improved after treatment than those before the operation (P<0.05). Both BCVA and CMT were better in the combined group than those in the pure surgery group at 1, 3 and 6 months after the operation, and the differences were statistical (P<0.05)．The IOP was stable in both groups, and there was no
statistic difference at different time points in both groups and between the two groups (P>0.05). The inflammation reaction of anterior chamber in combined group was less than that in the pure surgery group(P<0.05)．
Conclusion23gauge miniinvasive vitrectomy combined with posterior subTenoncapsule injection of TA can reduce macular edema and improve visual acuity, and it is safe and effective for PDR.
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Published: 23 October 2018
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