Abstract: ObjectiveTo evaluate the clinical effect of nano-hydroxyapatite/polyamide 66 (n-HA/PA66) cage in the anterior spinal reconstructive surgery for spinal tuberculosis in children.MethodsA total of 23 children with spinal tuberculosis from January 2008 to December 2015 were performed anterior focus debridement and spinal reconstructive surgery by n-HA/PA 66 cage combined with spinal internal fixators. The tuberculosis located in thoracic vertebrae in 9 cases, thoracolumbar vertebrae in 9 cases and lumbar vertebrae in 5 cases. The preoperative Frankel classification was grade D in 14 cases and grade E in 9 cases.ResultsAll 23 were followed up for 9 to 36 months with an average of 12.6 months. The pain was relieved with the VAS sore decreasing from 7.2±1.3 preoperatively to 1.8±1.1 postoperatively (P<0.05). The symptom of tuberculosis was disappeared and the lesion was cured completely without recurrence. 14 cases with incomplete paraplegia restored from grade D to grade E of Frankel neurological classifications. The Cobb angle of involved vertebrae was corrected from 45.2°±2.5° preoperatively to 28.3°±2.6° postoperatively(P<0.05). There was no cage emersion, rupture and collapse in all cases. The fusion rate achieved 100% nine months after the surgery. The X-ray and 3D-CT showed slight sedimentation of the cage in 4 cases, but well bone fusion was achieved between the imbedded cage and terminal plate of adjacent vertebral body and internal fixation was reliability in all cases.ConclusionThe n-HA/PA 66 cage can restore and maintain the fusion segmental height and improve the bone graft fusion, and it is an ideal shoring and grafting material in the anterior spinal reconstructive surgery for spinal tuberculosis in children.
王强，罗为民，许宇霞，何友智，王永福. 纳米羟基磷灰石/聚酰胺66椎体支撑体在儿童脊柱结核前柱重建手术中的应用[J]. 中国现代手术学杂志, 2017, 21(4): 279-282.
WANG Qiang,LUO Wei-min,XU Yu-xia,HE You-zhi,WANG Yong-fu. Application of Nano-Hydroxyapatite/Polyamide66Cage in the Anterior Spinal Reconstructive Surgery for SpinalTuberculosis in Children. Chinese Journal of Modern Operative Surgery, 2017, 21(4): 279-282.
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2017, Vol. 21 
