Abstract: ObjectiveTo observe the effectiveness of the clinical application of the artificial dermis combined with autologous skin surgery grafting for wound repair.MethodsThere were 56 cases needed wound repair who were hospitalized in our department from August 2011 to May 2016.At first,expansion removal of necrotic tissue or resection of scar tissue with dysfunction and deformed appearance was carried out,and then the artificial dermis was covered on the wound.After 3~4 weeks of artificial dermal vascularization,the second phase was treated with autologous skin graft.ResultsAll the wounds of 56 cases were completely repaired.There were 4 cases of dermal infection caused by dermal dissolution,and an artificial dermis re-plantation was needed.There were 2 cases failed in dermal tissue formation,and then the skin flap repair was used.The remaining cases successfully finished the two steps of operation plans.The healing effect was similar to the autologous mid-thickness skin graft,and the injury of donor sites was slight in the artificial dermal repair.ConclusionsIt is a good choice of the artificial dermis combined with autologous skin graft in plastic surgery with good clinical effects in addition to the traditional reconstruction methods.
杨力,潘圣鑫,薛君荣,蒋鹏,郭贤钊. 人工真皮联合自体皮片移植在创面修复外科中的应用效果观察[J]. 中国现代手术学杂志, 2017, 21(2): 141-144.
YANG Li. Effect of Artificial Dermis Combined with Autologous Skin Transplantation on Wound Surface Repair. Chinese Journal of Modern Operative Surgery, 2017, 21(2): 141-144.
[1]Yannas IV,Burke JF.Design of an artificial skin.I.Basic design principles[J].J Biomed Mater Res,1980,14(1):65-81.[2]Burke JF,Yannas IV,Quinby WC Jr,et al.Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury[J].Ann Surg,1981,194(4):413-428.[3]Suzuki S,Kawai K,Ashoori F,et al.Long-term follow-up study of artificial dermis composed of outer silicone layer and innercollagen sponge[J].Br J Plast Surg,2000,53(8):659-566.[4]陈欣,王晓军,王成,等.应用人工真皮和自体皮移植修复难愈创面[J].中华烧伤杂志,2009,25(6):444-447.[5]陈欣,王浩,戴允东,等.负压引流技术辅助人工真皮与自体皮移植修复关节开放和/或骨折处骨外露创面的临床研究[J].中华烧伤杂志,2015,31(2):93-97.[6]杜伟力,周业平,田彭,等.人工真皮修复骨外露创面23例效果评价[J].中国组织工程研究与临床康复,2011,15(3):495-498.[7]杨力,朱小平,郭贤钊,等.应用人工真皮修复大面积颅骨外露创面[J].中华整形外科杂志,2014,30(2):136-137.[8]王晓红,李叶扬,黄俊,等.植入式人工真皮联合自体刃厚皮片治疗烧伤瘢痕的效果[J].广东医学,2013,34(13):2035-2036.[9]陆树良.瘢痕形成机制及治疗对策[J].中华烧伤杂志,2013,29(2):130-133.