甲状旁腺全切加前臂自体移植术治疗继发性甲状旁腺功能亢进

doi:10.16260/j.cnki.1009-2188.2017.01.001

Chinese Journal of Modern Operative Surgery

2017, Vol. 21

Issue (1): 1-4 DOI: 10.16260/j.cnki.1009-2188.2017.01.001

Original Research

Clinical Effec of Total Parathyroidectomy and Parathyroid Autotransplatation in the Treatment of Secondary Hyperparathyroidism

LI Ke, ZHOU Yufan, HU Xianming

Departmemt of General Surgery, the First Hospital of Changsha, Changsha 410005，Hunan, China

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Abstract ObjectiveTo evaluate the clinical efficacy of total parathyroidectomy and parathyroid autotransplatation in the treatment of secondary hyperparathyroidism.MethodsClinical material of 16 cases of secondary hyperparathyroidism were collected and total parathyroidectomy and parathyroid autotransplatation orearm autotransplantation were performed. The serum level of iPTH, calcium, phosphorus and the numeric pain intensity scale(NPIS) were evaluated before surgery, after glands removal, 1 day, 7 days and 4 weeks after surgery. The imaging examination before surgery and pathological examination after surgery were also collected.ResultsThe total parathyroidectomy and parathyroid autotransplatation were completed in 13 cases (81.25%). There was significant decrease of the serum level of iPTH, calcium, phosphorus and NPIS (P<0.05 or P<0.01). The improvement of symptoms were remarkable effective(81.3%), effective(12.5%) and ineffective(6.25%) respectively.ConclusionThe total parathyroidectomy and parathyroid autotransplatation is an effective operation for the treatment of secondary hyperparathyroidism with low risk. The symptoms and biochemical parameters can be improved significantly.

Key words： secondary hyperparathyroidism total parathyroidectomy parathyroid autotransplatation parathyroid hormone

Received: 16 October 2016 Published: 25 May 2018

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李可，周宇帆，胡宪明. Clinical Effec of Total Parathyroidectomy and Parathyroid Autotransplatation in the Treatment of Secondary Hyperparathyroidism[J]. Chinese Journal of Modern Operative Surgery, 2017, 21(1): 1-4.

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http://www.surgerychina.com/EN/10.16260/j.cnki.1009-2188.2017.01.001 OR http://www.surgerychina.com/EN/Y2017/V21/I1/1

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