Chinese Journal of Modern Operative Surgery  2017, Vol. 21 Issue (5): 5-8 DOI: 10.16260/j.cnki.1009-2188.2017.01.002 |
| Clinical Research |
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| The Clinical Value of the Hepatic Lobectomy Combined with Radical Resection for Perihilar Cholangiocarcinoma |
| ZHANG Lei, WANG Lin, GENG Zhimin, WAN Yong, MENG Fandi, MENG Xiankui
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| Department of Geratic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China |
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Abstract ObjectiveTo investigate the clinical value of the hepatic lobectomy combined with radical resection of perihilar cholangiocarcinoma.MethodsFrom January 2010 to January 2013, a total of 72 patients with perihilar cholangiocarcinoma in our hospital were analyzed retrospectively. All 72 patients were divided into two groups according to surgical procedure： The control group (n=36) was treated with radical resection of perihilar cholangiocarcinoma, and the observation group (n=36) was treated with hepatic lobectomy combined with radical resection of peri hilar cholangiocarcinoma. The operation result, radical resection rate, postoperative complication rate and 1, 2, 3 year survival rate were compared between two groups.ResultsThe operation time and intraoperative blood loss in the observation group were significantly higher than those in the control group (（305.5±16.7）min vs. （244.3±15.8）min, (341.6±20.7)ml vs. （67.5±4.1）ml, P<0.05). There was no statistical difference in the hospital stays between two groups (P>0.05). The radical resection rate of the observation group was 77.8%, and was significantly higher than 27.8% of the control group (P<0.05). The postoperative complication rate of the observation group was significantly higher than that of the control group (36.1% vs. 13.9%, P<0.05). The survival rate of 1, 2, 3 year was 83.3%, 50% and 33.3% respectively in the observation group, and was remarkable higher than 52.8%, 22.2% and 8.3% respectively in control group (P<0.05).ConclusionThe surgery of hepatic lobectomy combined with radical resection can play an important role in improving the radical resection rate effectively and increasing the survival rate for perihilar cholangiocarcinoma.
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Published: 25 May 2018
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Corresponding Authors:
MENG Xiankui
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