Abstract: ObjectiveTo explore the anesthetic effect of modified laryngeal mask combined with dezocine for fiberoptic bronchoscopy.MethodsThere were 90 cases of patients with grade Ⅰ~Ⅱ of ASA were enrolled. They were randomly divided into three groups, with 30 cases in each. The patients in group A were given 2~3 μg/kg of fentanyl and 1~2 mg/kg of propofol for anesthesia induction, and then were inserted normal laryngeal mask. The patients in group B and C were given 0.1~0.15mg/kg of dezocine and 1~2 mg/kg of propofol for anesthesia induction, and then were inserted normal laryngeal mask and modified laryngeal mask respectively. The patients in the three groups were carried out fiberoptic bronchoscopy after anesthesia. It was recorded of the mean arterial blood pressure (MAP) and heart rate (HR) before anesthesia (T0), immediately after induction (T1), immediately after laryngeal mask insertion (T2), 5 minutes after bronchoscope insertion (T3), at the end of the bronchoscopy (T4) and laryngeal mask pulling out(T5), adverse reactions, and satisfaction with the anesthetic effect of the operators respectively.ResultsThe MAP and HR in group A at T1 were lower than that of groups B and C (P<0.05). But it was higher than that of group B and C at T2~T4 (P<0.05). The rates of intraoperative hypoxemia, intraoperative interruption, postoperative nausea, and postoperative vomiting in group A were higher than that of groups B and C (P<0.05). The intraoperative interruption rate of group B was higher than that of group C (P<0.05). The satisfaction rate of the anesthetic effect of group B and C was higher than that of group A (P<0.05).ConclusionThe application of modified laryngeal mask combined with dezocine for fiberoptic bronchoscopy has advantages such as hemodynamic stability, safety, less adverse reactions and so on, which is worthy of promotion in clinical treatment.
吴运斌,梁治辉,梁克诚,卢玲静,卢燕媚. 改良喉罩联合地佐辛用于纤支镜检查的临床观察[J]. 中国现代手术学杂志, 2017, 21(1): 69-72.
WU Yunbin, LIANG Zhihui, LIANG Kecheng, LU Lingjing, LU Yanmei. Clinical Observation of Modified Laryngeal Mask Combined with Dezocine for Fiberoptic Bronchoscopy. Chinese Journal of Modern Operative Surgery, 2017, 21(1): 69-72.
Ding Y, White PF. Comparative effects of ketorolac, dezocine, and fentanyl as adjuvants during outpatient anesthesia[J]. Anesth Analg, 1992,75(4):566571.
[6]
Pandit UA, Kothary SP, Pandit SK.Intravenous dezocine for postoperative pain: a doubleblind, placebocontrolled comparison with morphine[J]. J Clin Pharmacol, 1986,26(4):275280.
Yeo ST, Holdcroft A, Yentis SM, et al. Analgesia with sevoflurane during labour: i. Determination of the optimum concentration[J]. Br J Anaesth, 2007,98(1):105109.
Dockendorff C, Jin S, Olsen M, et al. Discovery of muopioid selective ligands derived from 1aminotetralin scaffolds made via metalcatalyzedringopening reactions[J]. Bioorg Med Chem Lett, 2009 ,19(4):12281232. doi: 10.1016/j.bmcl.2008.12.095.