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中国现代手术学杂志  2018, Vol. 22 Issue (3): 183-187    DOI: 10.16260/j.cnki.1009-2188.2018.03.006
  临床论著 |
颈椎管内巨长型神经鞘瘤的外科治疗
王军,何飞平,盖景颖
湖南省脑科医院脊柱外科, 长沙 410007
The Surgical Treatment of Giant and Long Schwannoma in Cervical Spinal Canal
WANG Jun, HE Feiping, GAI Jingying
Department of Spinal Surgery, Brain Hospital of Hunan Province, Changsha 410007, Hunan, China
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摘要 目的总结和分析巨长型颈椎管内神经鞘瘤的外科治疗效果和经验。方法回顾性分析2004年3月~2011年8月收治的9例颈椎椎管内巨长型(椎管内占位连续超过3个节段)神经鞘瘤病例,其中经颈后正中入路手术切除7例,前后联合入路2例。4例行显微镜下整块全切除,2例直视下行整块全切除,2例行分块全切除,1例未全切。5例采用后路侧块螺钉内固定系统重建,前后联合入路的2例均行后路钉棒和前路钛网内固定系统重建,2例未行内固定。结果本组术中失血500~1 150 ml,平均 (846±147)ml。术后伤口浅表感染1例,经外用莫匹罗星软膏、按时清创换药后于术后16 d愈合。术后病理均证实为神经鞘瘤。随访10~43个月,平均(23.6±6.4)个月。88.9%(8/9)的患者神经脊髓功能明显改善,VAS评分由术前的 (6.22±2.13)降至术后的 (2.89±2.11), JOA评分由术前的 (13.22±5.82) 降至术后的(6.44±4.67),手术前后VAS评分、JOA评分比较均有统计学差异(P<0.05)。影像学显示无颈椎不稳等现象发生,术后未见肿瘤复发及恶变。结论手术切除是颈椎管内巨长型神经鞘瘤的最佳治疗手段,但手术难度大、风险高、个体化明显。术前应根据肿瘤的部位及其与周围组织结构的关系制定合理的手术方案。
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WANG Jun
HE Feiping
GAI Jingying
关键词:  颈椎  椎管内肿瘤  神经鞘瘤,巨长型    
Abstract: ObjectiveTo analyze the surgical effect and experience of the giant and long schwannoma in cervical spinal canal.MethodsThe clinical data of nine cases with giant and long schwannoma (consecutively occupying more than three segments) in cervical spinal canal admitted from March 2004 to August 2011 were analyzed retrospectively. They were performed surgical intervention by cervical posterior approach in 7 cases and anteriorposterior combined approach in 2 cases. Total resection were performed in 8 cases, including 4 under microscope, 2 under direct vision and 2 of deblocking excision, and partial excision in one case. The screw internal fixation of the posterior lateral mass was applied in 5 cases, the combined internal fixation of posterior pedicle screw and anterior titanium mesh was in 2 cases, and internal fixation was not applied in 2 cases.ResultsThe intraoperative hemorrhage volume was 500 to 1 150 ml with an average of 846±147 ml. One patient was found superficial wound infection after the surgery. After 10 to 43 months followup (mean, 23.6±6.4 months), the neural symptoms of 88.9% of the patients were significantly improved. Radiography showed that there was no occurrence of cervical instability and no recurrence of the tumors after the surgery.ConclusionsSurgical resection is the best treatment for giant and long schwannoma in cervical spinal canal, but it is rather difficult, highly risky and obviously individualized as well. Preoperative reasonable surgical plan should be made necessarily according to the location of the tumor and the relationship between tumor and the surrounding structures.
Key words:  cervical vertebrae    intraspinal neoplasms    schwannoma, giant and long
               出版日期:  2018-06-26      发布日期:  2018-09-05      期的出版日期:  2018-06-26
ZTFLH:  R739.42  
作者简介:  王军,男,39岁,湖南省脑科医院脊柱外科副主任医师。
引用本文:    
王军,何飞平,盖景颖. 颈椎管内巨长型神经鞘瘤的外科治疗[J]. 中国现代手术学杂志, 2018, 22(3): 183-187.
WANG Jun, HE Feiping, GAI Jingying. The Surgical Treatment of Giant and Long Schwannoma in Cervical Spinal Canal. Chinese Journal of Modern Operative Surgery, 2018, 22(3): 183-187.
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http://www.surgerychina.com/CN/10.16260/j.cnki.1009-2188.2018.03.006  或          http://www.surgerychina.com/CN/Y2018/V22/I3/183
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