Please wait a minute...

中国现代手术学杂志  2018, Vol. 22 Issue (2): 90-94    DOI: 10.16260/j.cnki.1009-2188.2018.02.003
  手术学研究 |
开腹和微创肾部分切除术对孤立肾肾癌的应用效果比较
宋文斌,朱国栋,吴大鹏,杨志尚
西安交通大学第一附属医院,陕西西安 710061
Comparison of the Effects of Open and Minimally Invasive Partial Nephrectomy on Solitary Kidney Tumor
SONG Wen-bin, ZHU Guo-dong, WU Da-peng, YANG Zhi-shang
The?First?Affiliated?Hospital?of?Xi'an?Jiaotong?University,?Xi'an?710061,?Shaanxi,?China
下载:  RICH HTML  PDF (223KB) 
输出:  BibTeX | EndNote (RIS)      
摘要 目的 比较开腹和微创肾部分切除术(partial nephrectomy, PN)对孤立肾肾癌的应用效果。 方法 选取2012年1月至2016年8月我院收治的行PN治疗的49例孤立肾肾癌患者为研究对象,其中男38例,女11例,年龄38~80岁,平均(62.5±11.0)岁。根据手术方式分为常规腹腔镜组(n=15)、机器人腹腔镜组(n=11)和开放组(n=23),比较3组的基线资料和围手术期资料,对所有患者术后均进行定期的门诊随访,观察有无肿瘤复发及血清肌酐(serum creatinine, Scr)、肾小球滤过率估计值(glomerular filtration rate, GFR)、血红蛋白(hemoglobin, Hb)的变化。 结果 3组的基线资料、手术时间、术中输血及并发症的发生率比较,差异无统计学意义(P>0.05)。全部患者均成功完成手术操作,3组的术中失血量、热缺血时间(warm ischemia time, WIT)和住院时间比较,差异均有统计学意义(P<0.05),具体而言,术中失血量:开放组>常规腹腔镜组>机器人腹腔镜组;WIT:常规腹腔镜组>机器人腹腔镜组、开放组;住院时间:开放组>常规腹腔镜组>机器人腹腔镜组。全部患者随访5~61个月, 中位随访时间为23.5个月, 期间共有3例 (6.1%) 发现局部复发, 无一例远处转移者, 无瘤生存时间为 (22.3±15.5) 个月。3组的局部复发率、手术前后的Scr、GFR、Hb比较,差异无统计学意义(P>0.05)。 结论 与传统开放和常规腹腔镜下PN手术相比,机器人腹腔镜手术具有术中出血量少、WIT短、术后恢复快的优点,更加有利于保护残肾功能,应用效果最佳。
服务
把本文推荐给朋友
加入引用管理器
E-mail Alert
RSS
作者相关文章
宋文斌,朱国栋,吴大鹏,杨志尚
关键词:  肾部分切除术   机器人腹腔镜手术   肾细胞癌   孤立肾    
Abstract: Objective To investigate the effect of open and minimally invasive partial nephrectomy (PN) on solitary kidney tumor. Methods 49 patients with solitary kidney tumor underwent PN from January 2012 to August 2016 were enrolled for the study and included 38 males and 11 females. Their average age was (62.5±11.0) years, ranged from 38 to 80 years. All cases were divided into the routine laparoscopic group (n=15), the robot-assisted laparoscopic group (n=11) and the open group (n=23). The baseline data and perioperative data were compared among three groups. All patients were followed up regularly, observing the changes of serum creatinine (Scr), glomerular filtration rate estimation (GFR) and hemoglobin (Hb)Results There were no significant differences in baseline data, operation time, rates of blood transfusion and complications among three groups (P>0.05). All patients successfully underwent operation, and there were significant differences in intraoperative blood loss, warm ischemia time (WIT) and time of hospitalization among three groups (P<0.05). Specifically, the order of intraoperative blood loss, WIT and time of hospitalization was that the open group > the routine laparoscopic group > the robot-assisted laparoscopic group; the routine laparoscopic group > the robot-assisted laparoscopic group and the open group; the open group > the laparoscopic group > the robot-assisted laparoscopic group. All patients were followed up for 5~61 months whose median follow-up time was 23.5 months. A total of 3 cases (6.1%) were found with local recurrence, no one with metastasis, and tumor free survival time was (22.3±15.5) months. There were no significant differences in the local recurrence rate, Scr, GFR and Hb before and after operation among three groups (P>0.05). Conclusions Compared with traditional open and routine laparoscopic PN, robot-assisted laparoscopic surgery has the advantages of less intraoperative bleeding, shorter WIT and faster postoperative recovery, which is helpful to protect the residual renal function and has the best effect.
Key words:  partial nephrectomy     robot-assisted laparoscopic surgery     kidney tumor     solitary kidney
               出版日期:  2018-04-26      发布日期:  2018-08-14      期的出版日期:  2018-04-26
ZTFLH:  R692.11  
  R737.11  
基金资助: 国家自然科学基金面上项目(81672539)
通讯作者:  杨志尚,男,58岁,西安交通大学第一附属医院泌尿外科教授。   
作者简介:  宋文斌,男,36岁,西安交通大学医学院在读博士,西安交通大学第一附属医院泌尿外科主治医生。
引用本文:    
宋文斌,朱国栋,吴大鹏,杨志尚. 开腹和微创肾部分切除术对孤立肾肾癌的应用效果比较[J]. 中国现代手术学杂志, 2018, 22(2): 90-94.
SONG Wen-bin. Comparison of the Effects of Open and Minimally Invasive Partial Nephrectomy on Solitary Kidney Tumor. Chinese Journal of Modern Operative Surgery, 2018, 22(2): 90-94.
链接本文:  
http://www.surgerychina.com/CN/10.16260/j.cnki.1009-2188.2018.02.003  或          http://www.surgerychina.com/CN/Y2018/V22/I2/90
[1] Mues AC, Korets R, Graversen JA, et al. Clinical, pathologic, and functional outcomes after nephron-sparing surgery in patients with a solitary kidney: a multicenter experience[J]. J Endourol, 2012, 26(10): 1361-1366.|[2] Haber GP, Lee MC, Cmuzet S, et al. Tumor in solitary kidney: laparoscopic partial nephrectomy VS laparoscopic cryoablation[J]. BJU Int, 2012, 109(1): 118-124.|[3] 张雪培, 任选义. 复杂性肾脏肿瘤开放手术保留肾单位的技术探讨(附光盘)[J]. 现代泌尿外科杂志,2015,20(3):141-143.|[4] Sascha Paherni k, 朱捷, 隗英琦, 等. 孤立肾模型中热缺血时间对肾部分切除术后长期肾功能的影响[J]. 微创泌尿外科杂志, 2014, 3(2): 68-72.|[5] 毕新刚, 肖振东, 寿建忠, 等. 孤立肾肾癌行热缺血肾部分切除术后肾功能的变化[J]. 医学研究杂志,2013,42(6):191-193.|[6] Hersey P, Poullis M. Does the administration of mannitol prevent renal failure in open abdominal aortic aneurysm surgery?[J]. Interact Cardiovasc Thorac Surg, 2008, 7(5): 906-909.|[7] Power NE, Maschino AC, Savage C, et al. Intraoperative mannitol use does not improve long-term renal function outcomes after minimally invasive partial nephrectomy[J]. Urology, 2012, 79(4): 821-825.|[8] 王俊. 腹腔镜与开放肾部分切除术的对比研究[D]. 山东大学,2013.1-50.|[9] Shiroki R, Fukami N, Fukaya K, et al. Robot-assisted partial nephrectomy: superiority over laparoscopic partial nephrectomy[J]. Int J Urol, 2015, 23(2): 122-131.|[10] 刘竞, 李波, 李利军, 等. 机器人辅助腹腔镜下孤立肾肾部分切除术的临床研究[J]. 中华泌尿外科杂志,2016,37(4):251-254.|[11] Ching CB, Lane BR, Campbell SC, et al. Five to 10-year follow up of open partial nephrectomy in a solitary kidney[J]. J Urol, 2013, 190(2): 470-474.
No related articles found!
No Suggested Reading articles found!
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed