Abstract: ObjectiveTo explore the effect of vacuumassisted closure (VAC) technique in the treatment of diabetic foot ulcer.MethodsA total of 41 cases with diabetic foot ulcer were analyzed retrospectively from March 2014 to July 2015. All patients were divided into two groups: 24 cases of observation group were treated by VAC technique, and 17 cases of control group were treated by conventional dressing treatment. Therapeutic effect was compared between the two groups.ResultsThe preparation duration of wound surface was （15.7±8.6）d and （29.3±10.8）d respectively in the observation group and control group, there was statistical difference in preparation duration between two groups (P<0.05). The result was revealed cure in 19 cases, improved in 4 cases and invalid in 1 case in the observation group, and cure in 7 cases, improved in 5 cases and invalid in 5 cases in the observation group. The effective rate was 95.83% in the observation group, and was higher than 70.59% of the control group （P＜0.05）.ConclusionThe VAC technique can play a valid role to improve and accelerate wound healing in patients with diabetic foot ulcer， and it is worthy to be popularized.
邰菂，张承德，王进勇，吴德勇，徐向荣. 封闭式负压引流治疗糖尿病足溃疡的疗效[J]. 中国现代手术学杂志, 2017, 21(1): 52-54.
TAI Di, ZHANG Chengde, WANG Jinyong, WU Deyong, XU Xiangrong. Vacuumassisted Closure Technique in the Treatment of Diabetic Foot Ulcer. Chinese Journal of Modern Operative Surgery, 2017, 21(1): 52-54.
Jiang Y, Wang X, Xia L, et al. A cohort study of diabetic patients and diabetic foot ulceration patients in China［J］. Wound Repair Regen, 2015, 23(2):222230. doi: 10.1111/wrr.12263.
Fleischmann W, Strecker W, Bombelli M, et al. Vacuum sealing as treatment of soft tissue damage in open fractures［J］. Unfallchirurg, 1993, 96(9):488492.
［5］
Argenta LC, Morykwas MJ. Vacuumassisted closure: a new method for wound control and treatment: clinical experience［J］. Ann Plast Surg, 1997, 38(6):563576.
［6］
Morykwas MJ, Argenta LC, SheltonBrown EI, et al. Vacuumassisted closure: a new method for wound control and treatment: animalstudies and basic foundation［J］. Ann Plast Surg, 1997, 38(6):553562.
［7］
Weed T, Ratliff C, Drake DB. Quantifying bacterial bioburden during negative pressure wound therapy: does thewound VAC enhance bacterial clearance?［J］. Ann Plast Surg, 2004, 52(3):276279.
［8］
Saxena V, Hwang CW, Huang S, et al. Vacuumassisted closure: microdeformations of wounds and cell proliferation［J］. Plast Reconstr Surg, 2004, 114(5):10861096.
［9］
Banwell P, Téot L. Topical negative pressure (TNP): the evolution of a novel wound therapy［J］. J Tissue Viability, 2006, 16(1):1624.
2017, Vol. 21 
