Abstract: Abstract:ObjectiveTo investigate the effect of pulmonary artery reconstruction with autologous pericardial or azygos vein graft patch on postoperative complications and prognosis of patients with central lung cancer.MethodsThe clinical data of 98 patients with lung cancer who underwent surgical treatment in our hospital from January 2013 to January 2015 were retrospectively analyzed. According to the surgical methods, they were divided into the pneumonectomy group (47 cases) and the pulmonary artery reconstruction group (51 cases). The pulmonary function such as forced expiratory volume in one second(FEV1), forced vital capacity(FVC), maximal voluntary ventilation(MVV), transfer factor for carbon monoxide of lung(TLCO), and operative related indicators, postoperative complications and survival rates were compared between the two groups.
ResultsThere was no significant difference in FEV1, FVC, MVV and TLCO between the two groups before operation (P=0.947,0.710,0.608,0.858). The above indexes significantly decreased in the two groups 2 months after operation (P<0.05), and the above indexes in the pulmonary artery reconstruction group were significantly higher than that of the pneumonectomy group (P<0.001). Operation time, intraoperative bleeding volume, thoracic drainage volume, postoperative offbed interval and hospitalization time of the pulmonary artery reconstruction group were significantly lower than that of the total pneumonectomy group (P=0.027 or P<0.001). There was no significant difference in the number of lymph node clearance between the two groups (P=0.440). The incidence of postoperative complications in pulmonary artery reconstruction group was significantly lower than that of the pneumonectomy group (9.80% vs. 25.53%，P=0.040). There was no significant difference in the total survival rate between the two groups (HR=0.522, 95%CI ［0.241，1.130］, P=0.095), and the progression free survival rate in the pulmonary artery reconstruction group was significantly higher than that of the pneumonectomy group (HR=0.471, 95%CI ［0.237，0.935］, P=0.031).ConclusionPulmonary artery reconstruction with autologous pericardial or azygos vein graft patch can significantly improve the pulmonary function, alleviate surgical trauma, shorten recovery time, reduce postoperative complications and improve the prognosis for the central lung cancer patients.
赵振山, 李海洋, 赵振兴, 代岱, 郝孟辉. 自体心包奇静脉补片肺动脉重建对中心型肺癌患者术后并发症和预后的影响#br#[J]. 中国现代手术学杂志, 2018, 22(4): 285-290.
ZHAO Zhenshan, LI Haiyang, ZHAO Zhenxing, DAI Dai, HAO Menghui. Effect of Pulmonary Artery Reconstruction with Autologous Pericardial or Azygos Vein Graft Patch in Patients with Central Lung Cancer#br#
#br#. Chinese Journal of Modern Operative Surgery, 2018, 22(4): 285-290.
2018, Vol. 22 
