Abstract: Objective To discuss the feasibility and safety of laparoscopy assisted trans-anal surgery for rectal tumor. Methods The clinical data of 24 cases performed laparoscopy assisted trans-anal tumor resection from February 2015 to February 2017 were reviewed. The distance between tumor to anocutaneous line was (6.2±2.5)cm, and the diameter of tumor was(1.5±0.9)cm. Results All 24 patients were accomplished the surgery successfully, including 12 cases of rectal adenoma, 6 cases of high grade intraepithelial neoplasia and 6 cases of rectal cancer (4 of T0, 1 of T1 and 1 of T2 ). The mean operation time was (35.2±15.5) min, mean blood loss was (20.5±8.8) ml, and the postoperative hospital stays was 3 to 9 days. One case of T1 invaded submucosa 1/3 was carried out reoperation of laparoscopic colorectal cancer resection, 1 case of T2 invaded mucosal muscularis gave up the reoperation and lost to follow-up after surgery. 23 cases were followed up for (18±6) months. No tumor recurrence and metastasis was found. Conclusions Laparoscopy assisted trans-anal surgery is simple for treatment of rectal tumor. On the premise of reasonable selection of indication, it can achieve an ideal therapeutic effect.